Friday, November 29, 2019
Monday, November 25, 2019
Perfect Gym essays
Perfect Gym essays Every person in the world would like to have a perfect body. In order to have a healthy and a strong body, people would need to consider going to a gym to work out. What do such people expect of a gym? Certainly, patrons would expect a wide selection of equipment available in a gym. Patrons would enjoy a well-educated staff who knows everything people want to know about working out. The Bally Total Fitness, located on the Boulevard, is a perfect match for that. Patrons will definitely enjoy working out at the Bally Total Fitness. What kind of environment would patrons expect? Patrons will find the Bally Total Fitness clean, well organized, and suitable for working out. First of all, patrons will appreciate a wide selection of equipment available to them. Whether they like to use machines or free weights to achieve their goals, Bally Total Fitness is right for them. For example, patrons have a choice of inclined, declined, and regular bench press available to them. The gym has about 8 machines for each part of the body. The gym has 3 machines of the same kind, so patrons dont have to wait for someone to get finished with their work out. Ballys has about 5 set of dumbbells for each weight, so up to 5 people can work out at a time. Patrons will appreciate the wide selection of equipment offered to customers. Second of all, patrons would enjoy the staff, who can assist them with their work out. The Bally Total Fitness has 12 trainers on duty at a time. Trainers walk around and ask everyone if they would like help. For example, trainers are there to spot people bench pressing. Trainers give patrons hints on how to work certain muscles. Trainers can also design a healthy diet for one to follow. Patrons would enjoy the staff working at the Bally Total Fitness located on the Boulevard. Finally, patrons will appreciate the environment. Patrons will find the gym clean. The machines are cleaned every 15 ...
Friday, November 22, 2019
The UK Constitution Essay Example | Topics and Well Written Essays - 1500 words
The UK Constitution - Essay Example Critically evaluate this statement, supporting your evaluation with appropriate examples and authority.â⬠A Constitution is normally defined as the basic framework by which a state is governed. It usually outlines, in broad terms, the powers of a state as well as their limitations vis-a-vis the rights of its citizens. Some of the broad classifications of constitutions are: written or unwritten; republican or monarchical; flexible or rigid; unitary or federal; supreme or subordinate, and; underpin by separation of powers principle or fused powers. 1 The UK Constitution is one of the few constitutions in the world that is characterised as written but uncodified although some see it as unwritten. It is sourced from statutes, judicial decisions, old legal codes, relevant legal textbooks such as those authored by Dicey and Anson, in addition to unwritten ones such as common law and convention. 2 The nature of the UK Constitution, however, cannot be thoroughly understood by a mere ide ntification of these sources, but one must travel back in time and study the countryââ¬â¢s history, its type of government and relevant legal concepts such as Parliamentary Sovereignty to fully understand its nature. Moreover, a correct understanding of its nature disproves the criticism that the rules and practices underpinning the governmentââ¬â¢s operation are unconstitutional because they were not made specifically enforceable by a document. The UK Constitution is characterised as largely written, although some see it as unwritten, but uncodified, a constitutional monarchy, flexible, unitary, supreme, and operates under the fused power principle.3 The fact that it has not been reduced to simple terms in one single written document, however, makes it lacking in simplicity and comprehensiveness. Thes underlying rules and principles of the UK Constitution, therefore, have to be gleaned, extracted and made sense of from a number of sources without guaranty that consensus as to their meaning will be reached. 4 These sources include: the Magna Carta 1215, which clipped the monarchical powers; the Bill of Rights 1609, which created the constitutional monarchy; Act of Union 1707 creating Great Britain by uniting England and Scotland; Representation of the People Act 1832, which restructured the electoral laws of the country; Parliament Act 1911, which reduced the power of law-rejection of the Lords to a two-year delay; Life Peerage Act 1958, reformed the House of Lords; Representation of the People Act 1969, which made 18 the minimum voting age, and; House of Lords Act 1999 that further reformed the House of Lords. 5 Aside from statutes, other sources of the UK Constitution also include prerogative powers or powers traditionally exercised by the Crown, most of which, at present, had been devolved to ministers on behalf of the Crown; judicial decisions or case law; convention, whose informal form often make it a source of disputes; and texts and other seconda ry sources. 6 To assail the constitutionality of rules and principles because of the absence of a document that compels their legal enforceability is to reject the distinction between written and rigid constitutions on the one hand, and customary and flexible constitutions, on the other. It implies a rejection of unwritten, codified and rigid constitutions such as those of the Romans and the ancient Greece, for example. In contemporary times, New Zealand and Israel, aside from the UK, have only partly codified constitutions. 7 The legitimacy of the Westminster model of government implies the legitimacy of the UK Constitution and all appurtenant rules and principles that are necessary for its enforceability. Under the Westminster model, power is concentrated in the hands of the legislature as
Wednesday, November 20, 2019
Career action plan Coursework Example | Topics and Well Written Essays - 2250 words
Career action plan - Coursework Example It will also have a detailed analysis of the skills/knowledge and experience that would be expected from the particular candidate aspiring for a job. The report further progresses with the development of the CV and the covering letter preparation that would be prepared to demonstrate the skills/knowledge and experience in order to apply for a graduate level job. After that the report will exhibit the gap analysis where the current knowledge and the skills of the applicants will be matched with the requirement that has been identified in the research. At this stage, an attempt will be made to identify the areas where the candidate lacks. The preparation of the career action plan will be carried out where the candidate will show his commitment in order to plug the lacuna. At this section, personal development planning and career related activities will be undertaken. A short conclusion of the overall report will be presented to the reader in order to reflect the feeling on completion o f the overall assignment and exhibit an understanding of the intention to use the career action plan. Since several years the marketing job has been extremely competitive. The marketing industry is growing which is good news for those aspiring to make their careers on marketing. In order to overcome the tough times such as the recent economic slowdown, the companies seek people who can help them to get through this kind of situations. In this case, utilising money for marketing seems to be viable. However, there are certain drawbacks about these marketing jobs as well. Although the job profile seems to be attractive, the candidates have to face tough competition in this field. If the candidate seems to be incredibly hardworking and seeking challenges, then he can get involved into the marketing jobs. As the industry is growing there seems to be greater demand for
Monday, November 18, 2019
Finance Management Essay Example | Topics and Well Written Essays - 4500 words - 1
Finance Management - Essay Example The paper also assesses loans for the investment proposal and two suitable alternatives have been discussed. Analysis of Current Financial Performance: Ratio analysis has been used here to identify the companyââ¬â¢s position in terms of the profitability, efficiency, liquidity and financial structure. (Drury, 2005) Here the paper analyses the financial results of the four divisions over the past three years, based on which the business improvements in terms of the aid planning, control and performance management in the future have been discussed. The results are as discussed below: Profitability: Based on the profitability ratios, it has been noted that the Quality Product Division has seen an improvement in terms of the net profit margins. The company has moved from a loss to a profit of almost 3.36% which shows growth. Also the Return on Equity has also grown from a negative result in 2007 to almost10% which is close to the companyââ¬â¢s required rate of return. The gross pro fit margin for the company however has been stable. Quality Products Division
Saturday, November 16, 2019
Dents Disease: Symptoms, Genetics, and Treatments
Dents Disease: Symptoms, Genetics, and Treatments Dents Disease Alessander Leyendecker Junior Clinical Aspects Dents disease is a recently characterized syndrome caused by a genetic mutation that leads to a renal tubular disorder and is characterized by manifestations of proximal tubule dysfunction. The proximal tubule is responsable for the reabsorption of sodium, potassium, calcium, glucose and low-molecular-weight proteins (like retinol binding protein and à ±1 microglobulin and à ²2 microglobulin) and for the secretion of ammonia, toxins, drugs and H+. Therefore, a proximal tubule dysfunction like Dents disease is characterized by low-molecular-weight proteinuria (excretion of low-molecular-weight proteins in the urine), hypercalcinuria (high concentration of calcium in the urine), nephocalcinosis (deposition of calcium salts in the renal parenchyma), nephrolithiasis (formation of crystalline aggregates that can develop anywhere along the urinary tract) and progressive renal failure. Low-molecular-weight proteinuria represents the most common symptom of Dents disease (Devuyst Thakker, 2010). Mapping: A higher disease severity in males and a lack of male to male transmission were identified by an analysis of 5 unrelated British families. The fact that females may show a milder phenotype suggests an X-linked recessive inheritance. The locus position on chromossome Xp11 was identified by linkage analysis of 2 3-generation families with Dent disease by Pook et al. (1993). Twenty X-linked polymorphic markers were used and the Linkage was established between Dents disease and the Xp1l 1 loci ARAFI (Z max = 5.42, 0 = 0.000), DXS426 (Z max = 3.61, 0 = 0.000), DXS255 (Z max = 5.48, 6 = 0.000) and DXS988 (Z max = 4.25, 0 = 0.045) to determine a locus order. In addition, DXS255 has presented a microdeletion in the affected members of one family, allowing the localization of Dents disease to Xp11.22 (Pook et al., 1993). Furthermore, another proximal renal tubular disorder associated with nephrolithiasis in a North American family and referred to as X-linked recessive nephrolithiasis has also been mapped to Xpl1.22. Suggesting that maybe there is one gene causing both X-linked recessive nephrolithiasis and Dents disease. Molecular Genetics: A study conducted by Fisher et al (1994) found a microdeletion in one Dentââ¬â¢s disease kindred, allowing the identification of the gene CLCN5 as a candidate. Furthermore, an investigation of 11 kindreds with renal tube disorders indentified 3 nonsense, 4 missense, 2 donor splice site mutations, 1 intragenic deletion and 1 microdeletion in CLCN5 gene (Llyod et al., 1996). Furthermore, Hoopes et al. (2005) indentified that some patients with Dents disease suffer from extra-renal symptoms such as cataract, mild intellectual impairment and hypotonia. Shared mutations in OCRL1 with the oculo-cerebrorenal syndrome of Lowe were identified in these patients. The presence of such extra-renal symptoms with mutations relating to Lowe syndrome is known as Dent disease 2. A research conducted by Bà ¶kenkamp et al. (2009) showed that low-molecular-weight proteinuria was a constant feature in all both Dent disease 1, Dent disease 2 and oculo-cerebrorenal syndrome of Lowe. However, there was a wide overlap in most of the other symptoms of the proximal tubulopathy. Nephrocalcinosis was observed more frequently in patients with Dents disease 1 than those with Dents disease 2 and Lowe syndrome; aminoaciduria, renal tubular acidosis, and renal failure was observed more frequently in patients with Lowe syndrome than patients with Dent-disease 1 and Dent disease disease 2. Genetics: All these findings have demonstrated that both Dent disease 1 and Dent disease 2 are a X-linked recessive inherited condition, caused by mutations in the OCRL1 (Dent disease 2) or CLCN5 (Dent disease 1) genes. These genes are located on chromosome Xp11.22 (Dent disease 1) and Xq25 (Dent disease 2). Mutation in CLCN5 are responsible for about 60% of the cases of Dent disease and mutation in OCRL are responsible for about 15% of the cases of Dent disease (Hoopes et al., 2004). So, nearly 25% of the cases of Dent disease do not have a known disease-causing mutation in OCRL or CLCN5, implying another genetic heterogeneity. Due to the fact that Dents disease is a X-linked recessive disorder, the disease is generally found in males only. Females carriers may show a milder phenotype. Furthermore, the disease may be present in early childhood (Devuyst Thakker, 2010). To date around 250 families with Dent-1 disease and about 50 patients with Dent-2 disease have been reported (Ludwig, Levtchenko Bà ¶kenkamp, 2014). The diagnosis of Dents disease is always difficult due to the wide variability of clinical presentation and, occasionally, lack of family history. Therefore, the disorder is likely underdiagnosed and the prevalence of this disease in the population is still unknown. More than 200 Dents disease 1 patients withCLCN5defects have been described with several different disease-causing mutations all over the gene. The types of mutations includes missense (44%) and nonsense (26%) mutations, small deletions/insertions (15%) and splice defects (11%), with a few hotspots, usually affecting arginine codons. Large insertions/deletions can be detected in around 4%of the patients. However, OCRLmutations in Dents disease 2 patients are not uniformly distributed. Missense mutations are usually found in exons 8ââ¬â15 while nonsense or frameshift mutations very often affect exons (Ludwig, Levtchenko Bà ¶kenkamp, 2014). CLCN5 encodes the electrogenic Clà ¢Ã à »/H+ exchanger ClC-5. OCRL1 encodes a phosphatidylinositol bisphosphate (PIPà ¢Ã¢â¬Å¡Ã¢â¬Å¡) 5-phosphatase and mutations are also linked to the Lowe Syndrome. Mutations in any of these genes can culminate in the lack or dysfunction of these important proteins and result in the phenothype of Dents disease. Pathophysiology: The ability to reabsorb low-molecular-weight proteins and albumin that are ultrafiltered by the glomerulus are characteristics of the epithelial cells covering the proximal tubule portions of the nephron. This ability involves a process called receptor-mediated endocytosis. In the receptor-mediated endocytosis the particle to be endocytosed binds to specific receptor proteins concentrated at certain locations in the plasma membrane. Several types of receptors participate in the receptor-mediated endocytosis. These sites form a small depression in the plasma membrane that is covered by clathrin (a type of fibrous protein). After the binding of a ligand to plasma membrane-spanning receptors, a signal is sent through the membrane, leading to membrane coating, accumulation of the ligands into coated pits, and formation of a membrane invagination. The receptor and its ligand are then opsonized in clathrin-coated vesicles. The clathrin confers stability to the vesicle that are being transp orted into the cell. In the cytoplasm the vesicle loses its clathrin coverage and individual vesicles fuse to early endosomes. The acidification of endosomes by proton pumps ATP-dependent leads to the dissociation of the protein-receptor complex. This process allows the endosomes to fuse with the lysosomes through late endosomes. This acidification is reached by ATP-mediated transport of cytosolic H+ through the V-ATPase and demand an equal Cl conductance to preserve electroneutrality. It has been theorized that the H+ gradient can be neutralized by the C1C-5 action. In theory, ClC-5 provides an electrical shunt to neutralize the H+ gradient. Therefore, the vesicular acidification should be impaired by the loss of the endosomal Cl conductance mediated by ClC-5, resulting in the dysfunction of proximal tubule cells. To confirm this hypothesis, Piwon et al. (2000) created two distinct strains of ClC-5 knock-out (KO) mice which both have symptoms of the main characteristics of Dentâ⠬â¢s disease including manifestations of proximal tubule dysfunction like low-molecular-weight proteinuria. A reduced acidification of early endosomes in ClC-5-deficient mice have been demonstrated by in vitro experiments. However, ClC-5 is a 2Cl/H+ exchanger and not just a Cl channel, so the importance of this exchange activity for Dentââ¬â¢s disease was still unknown and needed to be assessed. In order to investigate this relevant question, Novarino et al. (2010) created a knock-in (KI) mouse presenting a point mutation in a important glutamate residue which transforms the exchanger into an uncoupled Cl channel that should help the endosomal acidification. The conventional ClC-5 KO mouse was subsequently compared with the KI mice. Acidification of the renal endosomes from wild-type and KI mice was regular, but greatly impaired in KO mice. Nevertheless, the same symptoms were indentified in both KI and KO mice, despite normal endosomal acidification and patients with Dentââ¬â ¢s disease, including low-molecular-weight proteinuria, hypercalciuria and hyperphosphaturia. Moreover, both the KI and KO mouse presented impaired proximal tubule endocytosis, indicating that proximal tubule dysfunction in Dentââ¬â¢s disease may happen in spite of the regular acidification of the endosomes. These findings indicate a function for a diminished endosomal Cl accumulation in Dentââ¬â¢s disease. Diagnosis: The clinical diagnosis of Dentââ¬â¢s disease is grounded on the presence of low-molecular-weight proteinuria, hypercalciuria, and at least one of the following characteristics: kidney stones, hematuria, nephrocalcinosis, renal insufficiency or hypophosphataemia (Hoopes et al., 2004). The clinical diagnosis can also be supported by nephrolithiasis and/or history of X-linked inheritance of renal Fanconi syndrome. The diagnosis can be confirmed by the recognition of mutation in both CLCN5 or OCRL1 by sequence analysis. Sequence analysis of affected males allows the identification of whole-gene deletions, multiexonic and exonic due to the lack of amplification is this case. Confirmation may also require deletion/duplication studies. It is imperative to previously identify the disease-causing mutation in the family when conducting a carrier test for at-risk relatives. The diagnosis of Dent disease 2, related with OCRL1 mutations, is more common than a diagnosis of Lowe syndrome when th ere are an absence of clinical symptoms and lack of severe intellectual deficit. Treatment: The reduction of hypercalciuria, prevention of nephrocalcinosis and kidney stones, and retardate the evolution of chronic kidney disease (nephrolithiasis) are the objectives of the current treatment. Thiazide diuretics in doses higher than 0.4 mg/kg/day have reducted urinary calcium excretion by more than 40% in males with Dent disease (Raja et al., 2002). However, side effects like hypokalemia, volume depletion, and cramping often occur. Similarly, we need to be cautious due to the fact that an increased hypercalciuria can result from the treatment of rickets with vitamin D. Furthermore, recent studies has been shown that a high citrate diet can slow the progression of chronic kidney disease in CLCN5 knockout mice (Cebotaru et al., 2005) and can be efficiently used to treat Dent disease. Genetic Counseling: The two types of Dentââ¬â¢s disease are X-linked. Therefore, men are affected more harshly. The father of an affected man will not have the disease or will he be a carrier of the mutation. The probability of transmitting the disease allele in each pregnancy is 50% if the mother of the proband is a carrier. Males who inherit the mutation will be affected and females who inherit the mutation will be carriers and will generally not be strongly affected. Affected men pass the disease-causing mutation to all of their daughters (who become carriers) and none of their sons. It is possible to conduct carrier testing for at-risk female relatives and prenatal testing for pregnancies at increased. Word count: 1673 References Blanchard A, Vargas-Poussou R, Peyrard S, Mogenet A, Baudouin V, Boudailliez B, Charbit M, Deschesnes G, Ezzhair N, Loirat C, Macher MA, Niaudet P, Azizi M: Effect of hydrochlorothiazide on urinary calcium excretion in Dent disease: an uncontrolled trial. Am J Kidney Dis 2008, 52:1084-1095. Bà ¶kenkamp A, Bà ¶ckenhauer D, Cheong HI, Hoppe B, Tasic V, Unwin R, Ludwig M. (2009). Dent-2 disease: A mild variant of Lowe Syndrome. J. Pediatr, 155, pp. 94-99, ISSN 0022-3476 Cebotaru V, Kaul S, Devuyst O, Cai H, Racusen L, Guggino WB, Guggino SE: High citrate diet delays progression of renal insufficiency in the ClC-5 knockout mouse model of Dentââ¬â¢s disease. Kidney Int 2005, 68:642-652. Devuyst, O., Thakker, R. V. (2010). Dentââ¬â¢s disease. Orphanet Journal of Rare Diseases. Fisher, S. E., Black, G. C., Lloyd, S. E., Hatchwell, E., Wrong, O., Thakker, R. V., Craig, I. W. (1994). Isolation and partial characterization of a chloride channel gene which is expressed in kidney and is a candidate for Dents disease (an X-linked hereditary nephrolithiasis). Human molecular genetics, 3(11), 2053-2060. Hara-Chikuma M, Wang Y, Guggino SE, Guggino WB, Verkman AS: Impaired acidification in early endosomes of ClC-5 deficient proximal tubule. Biochem Biophys Res Commun 2005, 329:941-946. Hoopes, R. R., Raja, K. M., Koich, A., Hueber, P., Reid, R., Knohl, S. J., Scheinman, S. J. (2004). Evidence for genetic heterogeneity in Dents disease.Kidney international,65(5), 1615-1620. Hoopes RR Jr, Shrimpton AE, Knohl SJ, Hueber P, Hoppe B, Matyus J, Simckes A, Tasic V, Toenshoff B, Suchy SF, Nussbaum RL, Scheinman SJ. Dent Disease with mutations in OCRL1. Am J Hum Genet. 2005;76:260ââ¬â267. doi: 10.1086/427887. Ludwig, M., Levtchenko, E., Bà ¶kenkamp, A. (2014). Clinical utility gene card for: Dent disease (Dent-1 and Dent-2).European Journal of Human Genetics. Lloyd, S. E., Pearce, S. H., Fisher, S. E., Steinmeyer, K., Schwappach, B., Scheinman, S. J., Thakker, R. V. (1996). A common molecular basis for three inherited kidney stone diseases. Nature, 379(6564), 445-449. Novarino G, Weinert S, Rickheit G, Jentsch TJ: Endosomal chloride-proton exchange rather than chloride conductance is crucial for renal endocytosis. Science 2010, 328:1398-1401. Pagon, R. A., Adam, M. P., Bird, T. D., Dolan, C. R., Fong, C. T., Stephens, K., Rossetti, S. (2012). Dent Disease. Piwon N, Gunther W, Schwake M, Bà ¶sl MR, Jentsch TJ: ClC-5 Cl-channel disruption impairs endocytosis in a mouse model for Dentââ¬â¢s disease. Nature 2000, 408:369-373. Pook, M. A., Wrong, O., Wooding, C., Norden, A. G. W., Feest, T. G., Thakker, R. V. Dents disease, a renal Fanconi syndrome with nephrocalcinosis and kidney stones, is associated with a microdeletion involving DXS255 and maps to Xp11.22. Hum. Molec. Genet. 2: 2129-2134, 1993. Raja KA, Schurman S, DMello R G, Blowey D, Goodyer P, Van Why S, Ploutz-Snyder RJ, Asplin J, Scheinman SJ. Responsiveness of hypercalciuria to thiazide in Dents disease. J Am Soc Nephrol. 2002;13:2938ââ¬â44 Wrong.O.M., Norden.A.G.W. and Feest.T.G. (1990) Quart. J. Med. 77, 1086-1087.
Wednesday, November 13, 2019
The Real National Treasure :: essays research papers
THE REAL NATIONAL TREASURE The United States, along with the allied forces of the world, is currently fighting to find Osama bin Laden as well as his organization, al Qaeda, in Afghanistan. The new declaration of the ââ¬Å"War on Terrorismâ⬠has withdrawn all boundaries that the terrorist organizations have been hiding behind. Although this war is a new idea to the average American Citizen, it is an old foe of the governments in most countries, which have already established antiterrorism and counter-terrorism task forces, but are now working together under an allied force. With the tightened security at the airports and military facilities, the counter-terrorism efforts are fighting back to counter the terrorists actions, but the key to fighting terrorism is to prevent the attacks from happening at all. à à à à à More than a majority of the American public supports this military action against countries that terrorize the United States. In fact according to a gallop poll, eighty-eight percent of Americans polled agree that the United States should take military action in retaliation for attacks on the World Trade Center and the Pentagon. The problem that is being faced by the world is how to avoid future attacks after the smoke clears from the current engagement. à à à à à There are two types of forces that are currently employed against terrorism and both have the same mission of fighting terrorism, with different applications. The antiterrorism force is used as a preventive action against future attacks while the counter-terrorism task force has many more post-action responsibilities. According to the Office of Counter-Terrorism, there are four policies being implemented as guidelines: ââ¬Å"Make no concessions to terrorists and strike no deals, bring terrorists to justice for their crimes, isolate and apply pressure on states that sponsor terrorism to force them to change their behavior, and bolster the counter-terrorism capabilities of those countries that work with the U.S. and require assistanceâ⬠. These steps are necessary to fight terrorism after the actions of horror have occurred, and the current Afghanistan action in search of the al-Qaeda members (including bin Laden) is an example of a counter-terrorism action. à à à à à In order to prevent future attacks, the United States must put a stronger emphasis on strengthening the antiterrorism forces. Putting more numbers on the membership board of this force is what is going to make headway in the ââ¬Å"War on Terrorismâ⬠. It is a lot more difficult to fight terrorism before the attacks have taken place, but history has already demonstrated that the oldest form of intelligence collection, human intelligence, can be used to fight an entire country.
Monday, November 11, 2019
DNA sequencing
Describe the limitations of traditional methods of Identifying bacteria. Traditional methods include judging by phenotypes characteristics. This could be a problem if two bacteria looked similar because they could easily be confused. Summarize the goal of each of the six parts of the lab. Sample Prep First we need to extract the DNA from the bacterial wall PC Amplification Create millions of copies of the initial DNA PC purification Filter out DNA from primers and enzymes Sequencing Prep Run more PC to make copies of DNA at various lengths DNA SequencingSequence machine runs gel electrophoresis to Identify nucleotides and determine sequence. Sequence Analysis Computer determines full DNA sequence which can be run and compared. Explain how fluorescent markers help determine a nucleotide sequence. Each nucleotide is assigned a certain color. Conclusion 1 How can scientists identify specific bacteria when they are amplifying and studying the same region of DNA In each species? They can identify it because there are unique sequences for each species. If you take a sample and find the DNA of it you can then compare it to the Dona's of known bacteria to discover what bacteria the sample is from
Saturday, November 9, 2019
How to Write a Marketing Resume That Will Help Land Your Dream Job
How to Write a Marketing Resume That Will Help Land Your Dream Job Writing a marketing resume isnââ¬â¢t easy. If you consider yourself a writer by trade, that sentiment might feel ironic. But, itââ¬â¢s true. Summarizing your history and skills in one page is tough, especially when your future career prospects hang in the balance. No pressure or anything, though. Fortunately, itââ¬â¢s a skill you can develop. This post is geared toward the following folks: College students and recent graduates looking for internships and entry-level jobs. Experienced marketers applying for their next opportunity. Marketing managers and HR professionals researching what to look for when hiring various marketing roles. Get ready to learn more about resuming writing than you might have thought you need to know. How to Write a Marketing Resume That Will Help Land Your Dream Job by @Ben_via Table of Contents: A Story Free Marketing Resume Template Are Resumes Still Important? What Makes Getting Yours Noticed So Difficult? What Does An Effective Resume Look Like? Planning Your Resume Formatting Your Resume Writing Your Resume Writing a Content Strategy Resume Writing a Social Media Marketing Resume Writing a Marketing Manager Resume Writing a Copywriting Resume Writing a Product Marketing Resume Writing a Public Relations Specialist Resume Writing an SEO Specialist Resume Writing a Marketing Project Manager Resume Writing a Paid Search/Social Resume Consider Creative Resume FormatsBut First, A Story â⬠¦ When I was in college, I was worried I wouldnââ¬â¢t find an internship, nor a full-time job following that. The economy was down and prospects were slim, so getting a foot in the door didnââ¬â¢t look particularly easy. I had also never written a resume before, and given the circumstances, I knew mine needed to be good. Fortunately, I did have some relevant experience built up from working at the student newspaper, tutoring, and various freelance gigs. After doing extensive research online, I did my best to put one together would convince a hiring manager I deserved an opportunity. In order to make sure my efforts were up to par, I made an appointment at the university career center for a resume review. I thought theyââ¬â¢d tear it apart, tell me everything that needed fixing, and send me on my way, ready to spend more time polishing it up. Instead, something else happened. After reading through my cover letter and resume, the student advisor looked up and said, ââ¬Å"This looks really good. In fact, weââ¬â¢re going to use this as an example for other students to follow. Nice work!â⬠That wasnââ¬â¢t the response I expected, but I was glad to take it. This is a 100% true story, and Iââ¬â¢m not sharing it to boast, either. Instead, Im sharing this experience to show thatà getting the job you want in this industry is an attainable goal. And it all starts with your resume. Steal My Marketing Resume Template Since then, Iââ¬â¢ve used roughly the same template for every job Iââ¬â¢ve applied for. Itââ¬â¢s gotten me several internships, and all three of my full-time jobs in the industry (in ecommerce, at a mid-sized agency, and now at ). Thereââ¬â¢s nothing fancy about it, but itââ¬â¢s clean, clear, and it works. Iââ¬â¢ve also adjusted it slightly to better fit different needs and experience levels. Hereââ¬â¢s everything the bundle includes (each one is included in both Microsoft Word and iWork Pages formats): Marketing Internship Resume Template Entry-Level Marketing Resume Template (Less Than 2 Years Experience) General Marketing Resume Template (2+ Years Experience) Marketing Manager Resume Template (8+ Years Experience) Download the whole bundle now. Itll help you save time on formatting, so all you need to do is fill it in. Job hunting for your next marketing opportunity? Snag these free #marketing resume templates: Are Resumes Still Important? In a word, yes. While LinkedIn is a vital tool for demonstrating your skills and expertise, hiring managers still typically want to see a resume. Itââ¬â¢s a big part of making a good first impression, so itââ¬â¢s important to get yours right. What Makes Getting Your Resume Noticed So Difficult? Hiring managers often have too many to look at. Most of the time, it really is that simple. According to Time, thatââ¬â¢s why the average resume only gets looked at for six seconds. In order to stand out, you have to make yours look exceptional. Avoiding Resume Mistakes There is nothing worse than sinking hours into the perfect job application, only to have your efforts undone by unforced errors, like typos (this is especially important for marketers and writing-based roles). From not catching spelling errors to failing to tailor your resume to the role youââ¬â¢re applying for, Thomas Frankà does an excellent job of summarizing what not to do in this video: What Does an Effective Resume Look Like? Itââ¬â¢s easier to replicate success when you have an example to follow. This template is closely based on one I created myself in college, and have used for the past decade. Itââ¬â¢s clean and simple, but it has worked well in my experience: Here's how to write and format an effective #marketing resumeLater, toward the end of this post, youââ¬â¢ll also see examples from around the web, tailored toward specific marketing disciplines. Depending on the type of role youââ¬â¢re applying for, the format might need to change slightly, or highlight different types of skills. Planning Your Resume Before you start writing, itââ¬â¢s a good idea to prepare all the information youââ¬â¢ll need. Youââ¬â¢ll need to round up previous work-related experience, contact references, summarize your strengths, and more. Know Who Will Be Reading Your Resume Every resume you send should be tailored toward the job youââ¬â¢re applying for. Generally, itââ¬â¢s a good idea to create one generic resume that you can adjust depending on the company or role youââ¬â¢re targeting. This doesnââ¬â¢t have to be rocket science. Start with these tips: Read the companyââ¬â¢s website. This will give you an idea what theyââ¬â¢re like. Research the company. What can you find out about them from news articles, blogs, or other third-party sources? Give their front desk a call or send an email. When it comes time to write a cover letter, it helps to address it to the right person. Find out who that is by making a quick inquiry (if that information isnââ¬â¢t easily available on a job listing). Recommended Reading: How to Find Your Target Audience and Create Content That Connects Assess Your Strengths Know what sets you apart as a candidate. Everyone is unique and possesses individual talents. Understanding them can help guide your career by emphasizing what youââ¬â¢re best at. If you havenââ¬â¢t before, itââ¬â¢s worth taking the StrengthsFinder self-assessment test. Itââ¬â¢s a book that comes with a code you can use to login to a web-based survey that will help you better understand your strong points. This short video summarizes how it works: The marketing teams at recently took this test. Hereââ¬â¢s what I learned: Having strengths in things like learning, ideation, and strategy are extremely useful for creating educational marketing content. Makes sense, right? I just wish I would have taken it sooner. Recommended Reading: How to Structure Modern Marketing Departments for Success Round Up References and Employment History If youââ¬â¢re new in your career, this may be a challenge if you donââ¬â¢t have much experience to lean on. When you submit a resume, include references on a separate sheet. Include the following information for each person: Name Company Job Title Phone Number Email Address Make sure you have permission to list each person on your application, so they arenââ¬â¢t surprised to get a phone call about you. Using people as references without permission is a major faux pas. Location. Location. Location. This step matters most if youââ¬â¢re applying for a job in another state or city, and will need to relocate. There are varying schools of thought on this, but this post will argue itââ¬â¢s best to be honest. Consider the following: If the job is within a commutable distance, use your own address. If youââ¬â¢d need to travel a longer distance for an interview, state that in your cover letter. If you can, consider using a friend or relativeââ¬â¢s address in the city. Formatting Your Resume So, what should this thing look like? Itââ¬â¢s an important question, and there are a handful of minor tweaks you can implement to improve formatting. Step 1. Pay Attention to Font Choices There are two types of fonts to pay attention to here: serifà and sans-serif. The graphic below illustrates the differences between the two: Source: Source: https://www.quora.com/What-is-the-difference-between-serif-and-sans-serif-typefaces There are key differences between serif and sans-serif fonts, and how they affect readability: According to Harshita Arora, sans-serif fonts offer a slight boost in readability. Thatââ¬â¢s why I used a sans-serif font on mine. Too many fonts is considered a negative for readability. Again, mine only uses one font (just in different formatting and sizing here and there). Using serif fonts isnââ¬â¢t going to ruin your resume if youââ¬â¢d really like to use them. Youââ¬â¢ll probably still get hired. But, for ease of reading and skimming, limit yourself to two fonts, and lean toward sans-serif. Recommended Reading: How to Work With Designers With Authentic Advice From 's Designer Step 2: Consider Narrower Margins for Wider Sentence Length Resumes need to include a lot of information in very little space (ideally, within one page). One way to squeeze in more detail about yourself while retaining a clean look is to use narrow margins. This helps you fit more text per line. If youââ¬â¢re using Microsoft Word, you can easily set wider margins by clicking on the Layout tab: Next, click Margins. Then, select Narrow: This is how the template included in this post sets its margins. Step 4: Use Bold Text Selectively Bolded text can help important elements of your resume stand out. Consider bolding items such as: Your college and major/minor. Previous companies and job titles. Thatââ¬â¢s about it. Too much bolding can easily look obnoxious. Writing Your Resume Youââ¬â¢re finally ready to start doing some actual writing. Hereââ¬â¢s how to make sure you nail it. Step 1: Put Your Contact Information at the Top A hiring manager will need to know the best way to contact you, and where to find more information about yourself and qualifications. Make their job easier by including each of these items: Name: Include your full name. Street Address: See the previous tip on location. Email Address: Use something that sounds professional. yourname@gmail.comà looks better than party_guy_2000@yahoo.comà or something else embarrassing. Twitter Bio: This is considered essential for a good number of marketing jobs. Only share it here if you tweet about topics relevant to marketing, or the companyââ¬â¢s industry where youââ¬â¢re applying. Portfolio: If you have an online portfolio, add a link here. You can also replace this with a blog or personal website URL, if itââ¬â¢s relevant to marketing. Some of this information is obvious. Other things like Twitter bios and portfolios, though, can be small enhancements that help you stick out as a candidate (as long as your social media presence is relevant and your portfolio is up to par). #Marketing #resume tip: include your contact information (along with your Twitter handle and...Step 2: Next, Include Your Education History In most cases, this will mean your college or university. Only list your high school if you didnââ¬â¢t attend college (no judgment hereI know people who have done well in digital marketing without attending or going into post-secondary education). Include the following: The type of degree you received: This means a Bachelor of Arts (BA) or Bachelor of Science (BS), Master of Arts (MA) or Master of Science (MS, or an Associates (AA). Your major and minor: This may be formatted differently depending on the details of your degree programs. For example, my degree was in Mass Communications, with an Emphasis in Print Journalism and Public Relations. Next, list your college:à Also include the month and year you graduated (or plan to graduate). A word about grade-point averages: in my experience, most marketing hiring managers donââ¬â¢t prioritize them. While high academic achievement reflects well on your work ethic, itââ¬â¢s your skills that are going to get you hired. So, should you bother listing your GPA? If your GPA is particularly strong, or you earned academic honors, then include them. Plus, if youââ¬â¢re in college and applying for a highly competitive internship, an employer may set a GPA threshold for applicants. If your grades werenââ¬â¢t great, youââ¬â¢re not doomed, as long as your portfolio demonstrates talent. Recommended Reading: How to Create an Awesome Online Course By Repurposing Old Content Step 3: List Professional Awards If youââ¬â¢re active in your community, or have a little bit of work-related experience, you may have been recognized for your efforts. Some examples might include: Academic honors for high-performing marketing students. Awards from professional or student organizations. Business and civic associations. Even if its not directly related to marketing, any sort of educational, business, or professional development awards youââ¬â¢ve earned are great ways to help you stand out. Step 4: Include Previous Speaking Engagements If you get the opportunity to speak at an industry event, take advantage of it. Itââ¬â¢s a great way to share your knowledge, and you often learn more about your topic by trying to explain it to others. They also show a willingness to volunteer your time to help others, and indicate a high level of competency in the field. Donââ¬â¢t have anything to put here? No worries. Just consider this tip something to think about. Have you spoken at an industry event? Include details on your resume.Step 5: Lay Out Your Most Relevant Technical Skills Once the general ââ¬Å"about yourselfâ⬠content is completed, itââ¬â¢s time to get down to your capabilities. If youââ¬â¢ve gone through college, have some work experience, or have a relevant side hustle, then you have some skills. However, itââ¬â¢s important to prioritize the ones that are most relevant to the job youââ¬â¢re applying for, and the ones where youââ¬â¢re most proficient. Here are some examples of skills you might need: Writing. Research. Proficiency with Word, Excel, and PowerPoint. SEO. Data analysis. Branding. Campaign strategy. HTML/CSS. Adobe CC (Photoshop, Illustrator, etc.) This is a general list, but you get the idea. The specific skills you might need to develop or highlight will depend on the specific type of role youââ¬â¢re applying for as well, which this post will cover later on. Now, what if youââ¬â¢re making a career change and donââ¬â¢t have what you think is relevant experience? In that case, itââ¬â¢s time to get creative, and determine how your existing skill set might transfer. Here are some examples: Are you a skilled researcher? Has your past work experience required a heavy amount of writing or design? Do you know how to analyze data and extract meaningful insights from it? Is project management and organized teams an area of strength for you? Recommended Reading: The 48 Most Essential Marketing Skills You Need to Be Successful in 2018 Step 6: List Your Professional Experience Here, start with your most recent relevant job position. Then, work your way backward chronologically. If you have too many to list, or if youââ¬â¢re applying for a senior role where you have lots of experience (say, maybe 10 years or more), then consider adding a second page to your resume. Otherwise, choose other areas to trim down, or include just your top three or four jobs. Be sure to include: Company. Job Title. Employment Dates. Once you have the basic information out of the way, add your responsibilities and accomplishments. While a hiring manager will want to know what you had on your plate at a past job, theyââ¬â¢ll be more impressed with what you actually achieved. So, make your experience stand out by doing this: Make it clear how your work positively impacted the business. Use statistics. ââ¬Å"Increased traffic by 75% and conversions by 8%â⬠sounds better than ââ¬Å"Increased traffic and conversions.â⬠Illustrate times where youââ¬â¢ve shown initiative. Maybe there was a problem you solved, or a major win you scored for the company without being asked.
Wednesday, November 6, 2019
Act 1 scene 5 has a very important role to play in Romeo ; Juliet Essay Example
Act 1 scene 5 has a very important role to play in Romeo ; Juliet Essay Example Act 1 scene 5 has a very important role to play in Romeo ; Juliet Essay Act 1 scene 5 has a very important role to play in Romeo ; Juliet Essay Act 1 scene 5 has a very important role to play in Romeo Juliet. Discuss its importance to the play and how Shakespeare makes this scene interesting and tense for the audience.Act 1 Scene 5 is a key scene in the play Romeo Juliet due to the events that happen in it. This is where Romeo Juliet first meet and fall in love with one another, a love that is not allowed given the antagonisms that exist between their families. Romeos friend Bonvolio had made his plan work. He planned to get Romeo to experience other beauties, or compare other women to his beloved Rosaline. This is also where the feud starts with Romeo and Tybalt because Tybalt is a Capulet and Romeo is a Montague. Tybalt is even angrier when he hears Romeos voice at his uncle Lord Capulets party because no Montagues are allowed. This by his voice, should be a Montague, Fetch me my rapier. The motivations that happen in the play show that the characters are doomed from the beginning because the forces greater than themsel ves. The forces include a long-running feud between the Montagues and the Capulets, something from which these lovers cannot escape no matter how hard they try.This scene has a great affect on all the other scenes in the play therefore I will be looking at how it is important. I will also be looking at how Shakespeare creates tension and interest for the audience.Act 1 Scene 5 comes at the end of the first act; this is because the audience are fully aware of the characters and their backgrounds. In this scene everyone and everything has been introduced to the audience and this tells us what will happen in the rest of the play. This scene also has dramatic irony because the audience knows more than the characters.In Romeo and Juliet the servants have to run round setting up the stage to start the next scene. We cannot be here and there too. This is because Romeo Juliet was written in 1595 and was set in the Globe theatre. There was not many props and equipment in Shakespeares day li ke there are today due to the fact that they never had much money. At the start of the scene the mood is happy, cheerful and tense. Lord Capulet is in a happy mood at the start of the scene because he is trying to marry his only daughter Juliet and his party is going well. He is happy and polite to his guests at the party talking in a poetic verse to show his importance. Welcome, gentlemen!In lines 53-91 there is a dramatic change in mood compared to the peaceful mood the audience previously see. The audiences tension and excitement is increased when Tybalt over hears Romeo talking. This by his voice, should be a Montague. He fills up with rage and shouts Fetch me my rapier. With this the audience are sitting on the edge of their seats. Romeos arrival changes the atmosphere and the audience are aware that it becomes tenser this is because the audience knows that Montagues arent welcome at a Capulets party.The scene is also romantic because this is the first time Romeo sets his eyes on Juliet and falls in love with her. For I neer saw true beauty till this night. Tybalt hears his voice and becomes angry Now by the stock and honour of my kin to strike him dead I do not sin. He goes and tells Lord Capulet that Romeo is here at his party. Tis he, that that villain Romeo. Lord Capulet is annoyed at him because he doesnt want anything to happen to his guests. Lord Capulet tries to calm Tybalt down, he tells Tybalt To say truth, Verona brags of him to be a virtuous and well governd youth. Tybalt becomes even more enraged; Ill not endure him, with this Lord Capulets attitude and manner suddenly changes towards Tybalt. He shall be endurd. With this Tybalt storms out of the room leaving the audience in suspense.When Romeo ; Juliet first meet this is vitally important in the rest of the play because if they didnt meet then the rest of the play wouldnt have happened. Romeo is very dazzled by Juliet and knows it is love at first sight. He expresses his inner feelings in a soliloquy which is controlled by his devotion and admiration for Juliet. O she doth teach the torches to burn bright? Shakespeare then uses a sonnet form with rhyming couplets to emphasise the love and romantic nature of the scene. So shows a snowy dove trooping with crows as yonder lady oer her fellow shows When Romeo and Juliet speak to each other the speech forms a sonnet; this is the 14 line poem which has alternate rhyme and ends in a rhyming couplet and this shows us the way they feel about each other. Did my heart love till now?. They start to talk about kissing. My lips two blushing pilgrims, ready stand to smooth that rough touch with a tender kiss. The audience knows that this is going to lead to something and know that they are about to share a kiss, which they do. Good pilgrim, you do wrong your hand to much. This shows religious images and also shows how deep and pure their love is. Romeo is in a world of his own, enraptured by the stunning beauty of Juliet. This creat es a romantic but also dangerous mood in the scene as the audience watch with anticipation and ask will they be caught?At the end of the scene, Shakespeare uses hints to make the audience think about future events in the play. Here Romeo and Juliet find out who the other actually is. After they exchange their love Juliet asks the nurse whom Romeo is, the nurse replies, His name is Romeo, and a Montague the only son of your great enemy. Juliet is so upset and shocked by this and says in confidence to the nurse, My only love sprung from my only hate! Too early seen unknown, and known too late! Prodigious birth of love it is to me, that I must love a loathed enemy.Romeo also finds this out and is very upset too. Is she a Capulet? This also creates a painful and upsetting atmosphere not only to the characters but also the audience. O dear account! My life is my foes debt. Romeo and Juliet talk about their lives being in each others hands; this reflects dramatic irony by showing what act ually happens to them at the end of the play because they both die for each others love. Swept away by the great passion of first love, their attempt to alter their family heritage and to unite in marriage causes their tragic deaths. Go ask his name. If he be married, my grave is likely to be my wedding bed.Romeo and Juliet are already keeping their love a secret and when she lies to the Nurse, the only person she trusts this shows the audience that they dont really care about anyone but themselves as they are in love and this sets the tone for their relationship. My only love sprung from my only hate. This is because she has fallen in love with the boy of her dreams. She now knows that he is a Montague and knows her family wont accept their love for one another.At the end of the scene I think that the audience become more anxious as they want to know what else happens in the scenes to come. If they did a play for a modern audience I think that it will work as it did in Shakespeare time because everyone enjoys love stories and they will have more equipment and props so the play will become more realistic.This scene is very important to the play because without it lots of other events wouldnt take place. This scene also has dramatic irony because the audience knows more than the characters as the audience are fully involved in the play. I like this scene in the play because I like the way Romeo and Juliet first meet and fall in love, I also like the way Shakespeares language is used to create characters, to add emotion and express meanings in the scene.
Monday, November 4, 2019
Are we as informed as we think we are Assignment
Are we as informed as we think we are - Assignment Example In the whole room, only their voices could be heard. One of the participants was a 45- year- old women called Heather Tay talks a lot by just repeating other people opinions by not reasoning out some meaningful thoughts just as the design and technology consultants (Ross, 2015). Her opinions are not liked by majority, but she feels used to being on the minority side. Tay, who is an African talks about an attack of Charlie Hebdo and someone, asked her the reason Christians especially the Catholic members can be made fun of but not the Muslimââ¬â¢s. The funny Tay answered the man in just but a simple way that it becomes easy to make excitement of majority compared to minority (Ross, 2015). Motivation entrepreneur of Tay and Rahman called Stuart Knight saw these and felt upset regarding it as lack of knowledge. Knight talks about on how technology has led to many sharing opinions but still majority are not well informed. Every person needs to take into account what is appropriate and meaningful both personally and to others. One needs to seek out new facts and puts them into practice. Thinking big about bigger questions is highly appreciated. One need to gather information from one source and puts it into a working memory that can only allow a maximum of four new information at
Saturday, November 2, 2019
Comparison between 17th & 18th centuries in France,England and America Term Paper
Comparison between 17th & 18th centuries in France,England and America - Term Paper Example The first concept that can be seen with the different pieces of architecture is the characteristics that are from each region. The first comparison which can be made is within England, specifically between the 17th and 18th centuries. In the 17th century, the style was based on the Baroque influences, which consisted of finding balance within each type of work. This was combined with the styles which were influenced by the political and cultural associations, inclusive of the Tudor monarch changing to a different political structure. The main concepts which were associated with the Baroque style began to change by the 18th century, specifically because of social and cultural associations. The political realms moved through revolutionary changes, specifically with an altered regime and order. This was combined with the Enlightenment and the Industrial Revolution, both which altered the materials used for architecture as well as the expectations of what should be included in the archit ectural styles. Many of the pieces of architecture began to change into experimentation with new materials, influences of structures that were romantic in style and which rebelled against the balance and form of the 17th century (Glennie, p 17). The examples of these changes show in the variety of architecture which was produced in England during the 17th and 18th century. The earlier work of the Hatfield House (1607) shows the Elizabethan style as well as how this related to the metaphor of the political and cultural structure, as seen in Figure 1. Figure 1: Hatfield House (1607) The architecture is one which is representative of the Elizabethan architecture first because of the distinct form of east and west wings as well as the central arches which remain even on both sides. The towers and the association with simplistic and ornate figures are also seen. The main concept was to keep an open region while offering a spacious area that represents the power of the political structure of the time. This was representative of the English time frame and the components which were associated with the 17th century balance and structure (Archer, 29). The changes in England can be seen with the progression of architecture, such as through the Chiswick House, (1725) seen in figure 2. Figure 2: Chiswick House (1725) The same references of balance are used with this, specifically with the association of columns and structure that was used. This is not only representative of the ideologies of the new political system and the thriving of the current status. Instead, there is a movement back to the ancient Greek structures for balance, seen through the columns and the dome that is used. The concept of architecture is one which combines several influences and uses experimentation of combining structures while keeping the balance as seen in the 17th century. The representation then shows the change in style with integration of different methods, specifically which is representa tive of the characteristics of the Industrial Revolution while keeping the same concept of balance and form as the central component of the time, which is specific to Neo ââ¬â Classicism (Archer, 37). The movement from balance and into a sense of Romanticism was also seen in other regions, including France and Colonial America. The French had a similar alteration into the Enlightenment and Romanticism in the 18th century, specifically because
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